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. 2020 Jul 18;11(2):219–226. doi: 10.1016/j.jceh.2020.07.003

Table 1.

Anthropometric and Biochemical Parameters of All Studied Animal Groups.

Group I negative control N = 10 Group II nontreated NAFLD group model N = 11 Group III positive control group N = 10 Group IV NAFLD + vitamin D supplement N = 14 ANOVA P value
Weight (gm) 194.80 ± 1.81 343.55 ± 5.80a 199.70 ± 2.68b 337.71 ± 3.72a,c <0.001
Height (cm) 21.26 ± 0.45 21.49 ± 0.32 21.23 ± 0.26 21.26 ± 0.34 0.94
BMI (gm/cm2) 0.43 ± 0.06 0.74 ± 0.07c 0.44 ± 0.03a,b 0.72 ± 0.07a,b <0.001
Hepatic index 0.05 ± 0.001 0.04 ± 0.001a 0.05 ± 0.001b 0.04 ± 0.001a,c <0.001
Insulin (μu/L) 25.54 ± 0.93 35.72 ± 0.92a 24.56 ± 1.69b 36.56 ± 1.10a,c <0.001
Glucose (mmol/L) 5.28 ± 0.35 7.88 ± 0.28a 4.69 ± 0.26b 7.72 ± 0.22a,c <0.001
HOMA-IR 0.33 ± 0.03 0.69 ± 0.03a 0.28 ± 0.03b 0.69 ± 0.03a,c <0.001
T Chol. (mmol/L) 2.73 ± 0.23 4.71 ± 0.30a 2.82 ± 0.23b 4.59 ± 0.38a,c <0.001
TG (mmol/L) 1.04 ± 0.08 1.33 ± 0.21a 1.00 ± 0.09b 1.23 ± 0.23a,c 0.001
LDL-C (mmol/L) 1.19 ± 0.17 2.34 ± 0.74a 1.00 ± 0.09b 1.72 ± 0.44a,c 0.001
HDL-C (mmol/L) 1.07 ± 0.10 1.53 ± 0.30a 1.01 ± 0.09b 1.89 ± 0.77a,c <0.001
Albumin (g/dl) 3.51 ± 0.02 3.41 ± 0.04 3.46 ± 0.02 3.48 ± 0.02 0.16
AST (U/L) 44.75 ± 1.03 57.07 ± 0.82a 45.62 ± 0.73b 56.66 ± 1.18a,c <0.001
ALT (U/L) 35.57 ± 0.76 46.34 ± 0.59a 35.41 ± 0.56b 45.57 ± 0.70a,c <0.001
ALP (U/L) 67.64 ± 1.10 66.58 ± 1.79 70.45 ± 1.51 64.40 ± 1.66 0.15
GGT (U/L) 8.97 ± 0.13 13.55 ± 0.30a 9.25 ± 0.12b 13.00 ± 0.34a,c <0.001
25 OHD3 (nmol/l) 13.24 ± 0.23 7.16 ± 0.37a 14.36 ± 0.36b 10.04 ± 0.26a,b,c <0.001
SMP-30 (pg/ml) 117.20 ± 0.87 83.21 ± 0.81a 116.70 ± 1.19b 84.18 ± 0.76a,c <0.001

Data are presented as mean ± standard deviation.

Statistical analysis was carried out using one-way analysis of variance (ANOVA) followed by Tukey's post-hoc analysis.

a

Significantly different from N.C value at P < 0.05.

b

Significantly different from NAFLD value at P < 0.05.

c

Significantly different from N.C + Vit D value at P < 0.05.