TABLE 1.

Summary of anatomical and functional parameters of the left atrium (LA) in the LAAT/TIA-neg and (left three columns) and LAAT/TIA-pos (right three columns) groups.

Subject Number	1	2	3	4	5	6
LAA Thrombus (or history of TIA)	No	No	No	TIAs	Yes	Yes
Sinus Rhythm	Yes	Yes	Yes	No	No	No
Mean LA Volume (ml)	86.6	70.1	115	145	157	180
Min. LA Vol. (VLA,min, ml)	59.6	49.0	87.2	119	150	157
Max. LA Vol. (VLA,max, ml)	108	91.2	145	155	165	205
Pre-A-wave Volume (VLA,pre-A, ml)	94.3	72.3	119	149	153	178
LA Sphericity	0.80	0.82	0.78	0.86	0.83	0.81
Global (LA EF) [(VLA, max- VLA,min)/ VLA,max]	0.45	0.46	0.40	0.23	0.091	0.23
Expansion Index [(VLA,max- VLA,min)/ VLA,min]	0.81	0.86	0.66	0.30	0.10	0.31
Passive EF [(VLA, max- VLA,pre-A)/ VLA,max]	0.13	0.21	0.18	0.039	0.073	0.13
Booster EF [(VLA, pre-A - VLA,min)/ VLA,pre-A]	0.37	0.32	0.27	0.20	0.020	0.12
Conduit Volume / LV Stroke Volume [1- (VLA,max- VLA,min) / SV]	0.33	0.50	0.41	0.46	0.80	0.63
PVs (ml)	43	38	51	36	17	49
PVd (ml)	65	58	60	52	63	94
PVs-PVd ratio	0.66	0.66	0.84	0.69	0.27	0.52
PVa (ml)	17	7.3	12	13	0.14	1.4
PVa duration (cycles)	0.11	0.11	0.13	0.12	0.039	0.068
A-wave duration (cycles)	0.22	0.25	0.30	0.18	0.21	0.23
PVa – A wave duration ratio	0.49	0.43	0.44	0.64	0.18	0.30
E/A ratio	1.64	2.36	3.03	2.05	3.86	3.65

Mean volume indicates time-averaged volume. EF, ejection fraction; PVs, blood volume that enters the LA during LV systole; PVd, blood volume that enters the LA during LV diastole; PVa, blood volume that exits the LA due to reverse flow volume through the pulmonary veins during atrial contraction; E/A ratio, ratio of peak mitral velocities during early diastole (E-wave) and atrial contraction (A-wave). Supplementary Figure 2 provides an example of these parameters.