Table 1.
Odds ratios (95% CI) for having localized, regional, or distant metastatic breast cancer versus carcinoma in situ based on total environmental quality index and individual covariates age at diagnosis, BMI, smoking status, and race using quartile 1 (worst environmental domain quality) as reference.
| Localized Breast Cancer |
Regional Breast Cancer |
Distant Metastatic Breast Cancer | |
|---|---|---|---|
| EQI | |||
| First Quartile (Best) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
| Second Quartile | 1.00 (0.97-1.02) | 1.01 (0.98-1.06) | 1.01 (0.98-1.05) |
| Third Quartile | 1.02 (0.99-1.04) | 1.05 (1.01-1.09) | 1.05 (1.01-1.09) |
| Fourth Quartile (Worst) | 0.99 (0.97-1.02) | 1.02 (0.97-1.06) | 1.00 (0.97-1.03) |
| p-trend | 0.488 | 0.042 | 0.054 |
| Age at Diagnosis | |||
| Age (10yr increments) | 1.03 (1.02-1.03) | 0.99 (0.98-0.99) | 1.01 (1.00-1.02) |
| BMI | |||
| Normal weight | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
| Underweight | 0.99 (0.94-1.04) | 1.01 (0.95-1.07) | 1.13 (1.02-1.26) |
| Overweight | 1.00 (0.98-1.02) | 1.00 (0.97-1.04) | 1.01 (0.97-1.04) |
| Obese | 1.01 (0.99-1.02) | 1.02 (0.99-1.05) | 0.99 (0.96-1.02) |
| Unknown | 0.98 (0.96-1.00) | 0.98 (0.95-1.01) | 1.03 (0.98-1.07) |
| Smoker | |||
| Current smoker | 1.05 (1.03-1.07) | 1.10 (1.07-1.14) | 1.15 (1.10-1.21) |
| Former smoker | 1.02 (1.00-1.03) | 1.04 (1.02-1.06) | 1.00 (0.97-1.03) |
| Never smoked | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
| Unknown | 1.00 (0.98-1.02) | 0.99 (0.97-1.02) | 0.94 (0.91-0.98) |
| Race | |||
| White | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
| Black | 0.97 (0.96-0.99) | 1.04 (1.03-1.06) | 1.09 (1.07-1.12) |
| Other | 1.01 (0.98-1.03) | 1.01 (0.96-1.06) | 1.06 (1.00-1.12) |
*
Bolded values are p<0.05