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. 2021 Mar 12;272(1):41–52. doi: 10.1007/s00406-021-01244-0

Table 2.

Laboratory test results of patients with COVID-19

Total Non-severe Severe P value
n = 51 n = 37 n = 14
IL-2 2.4 (2.3–2.6) 2.5 (2.3–2.6) 2.3 (2.3–2.6) 0.286
IL-4 2.0 (1.6–2.4) 2.1 (1.7–2.3) 2.0 (1.6–2.5) 0.874
IL-6 4.1 (2.8–5.8) 3.6 (2.6–5.6) 5.0 (3.7–9.7) 0.268
IL-10 2.8 (2.3–3.2) 2.8 (2.3–3.2) 2.7 (2.4–3.3) 0.908
TNF-α 1.9 (1.7–2.2) 2.0 (1.8–2.3) 1.9 (1.7–2.3) 0.466
IFN-γ 1.9 (1.6–2.4) 1.9 (1.6–2.4) 1.8 (1.6–2.1) 0.410
IL-6 > 2.9 37 (72.5%) 26 (70.3%) 11 (78.6%) 0.547
IL-6 < 2.9 14 (27.5%) 11 (29.7%) 3 (21.4%)
n = 54 n = 38 n = 16
CD3 + T 75.3 (68.3–81.7) 76.0 (67.8–81.4) 75.9 (69.8–84.5) 0.776
CD4 + T 46.4 (40.9–52.3) 46.4 (42.0–51.7) 48.6 (38.9–52.7) 0.691
CD8 + T 24.9 (17.7–27.8) 24.3 (16.8–27.5) 25.1 (21.2–30.2) 0.970
CD4 + /CD8 +  2.1 (1.5–2.6) 2.1 (1.5–2.9) 1.9 (1.5–2.3) 0.483
n = 77 n = 54 n = 23
Leukocyte count 4.8 (3.8–5.8) 4.6 (3.6–6.0) 5.1 (4.2–5.7) 0.581
Neutrophil count (109/L) 3.1 (2.1–3.6) 2.5 (2.0–3.6) 3.1 (2.4–3.8) 0.183
Lymphocyte count (109/L) 1.4 (1.1–1.8) 1.5 (1.2–1.9) 1.3 (0.9–1.6) 0.143
Count < 1.0 14 (18.2%) 7 (13.0%) 7 (30.4%) 0.078
Count ≥ 1.0 63 (81.8%) 47 (87.0%) 16 (69.6%)
Hemoglobin 127.5 (117.0–138.0) 130.0 (121.0–139.0) 117.0 (109.0–130.5) 0.008
Platelet count 193.5 (167.8–247.5) 193.0 (167.5–244.0) 215.0 (165.5–274.5) 0.457
Total bilirubin 12.8 (0.5–14.9) 11.9 (10.2–14.8) 13.1 (11.7–16.1) 0.201
Direct bilirubin 3.2 (2.8–3.8) 3.2 (2.8–3.8) 3.2 (2.8–3.5) 0.928
Total protein 64.2 (61.9–66.6) 64.2 (61.9–66.4) 63.6 (60.8–67.1) 0.839
Albumin 38.8 (36.0–41.6) 39.7 (36.8–42.7) 36.5 (35.1–40.8) 0.054
Globulin 24.8 (22.6–27.1) 24.2 (22.5–26.8) 26.2 (23.4–29.1) 0.059
Alanine aminotransferase 23.0 (15.3–43.8) 25.0 (17.5–44.5) 17.0 (13.0–36.0) 0.114
Aspartate transaminase 25.5 (19.3–34.5) 26.0 (20.0–33.0) 25.0 (18.0–35.0) 0.618
Lactate dehydrogenase 166.0 (138.0–195.5) 165.0 (134.0–196.5) 168.0 (140.0–194.0) 0.615
Creatine kinase 71.0 (50.5–98.8) 71.0 (57.5–88.5) 61.0 (42.0–131.0) 0.501
Urea nitrogen 4.1 (3.2–4.9) 3.8 (3.1–4.7) 4.3 (3.5–7.2) 0.022
Creatinine 72.5 (62.8–82.8) 72.0 (59.0–81.0) 75.0 (69.5–88.0) 0.078
Cystatin C 1.0 (0.9–1.21) 0.9 (0.8–1.2) 1.1 (1.0–1.4) 0.001
Fasting blood glucose 5.3 (5.0–5.8) 5.3 (4.9–5.8) 5.6 (5.2–5.9) 0.143
Total cholesterol 4.2 (3.5–4.7) 4.1 (3.3–4.8) 4.4 ((3.9–4.6) 0.459
Low-density lipoprotein 2.2 (1.8–2.6) 2.2 (1.6–2.6) 2.3 (2.0–2.5) 0.406
d-Dimer 0.4 (0.2–0.7) 0.3 (0.2–0.6) 0.6 (0.2–1.5) 0.060
Fibrinogen 3.7 (3.2–4.7) 3.6 (3.1–4.3) 4.4 (3.5–5.9) 0.020
Erythrocyte sedimentation rate 30.5 (18.8–62.5) 22.0 (17.0–59.5) 35.0 (24.0–75.5) 0.164
hs-CRP 1.6 (0.5–5.3) 1.3 (0.3–4.8) 2.2 (0.9–20.4) 0.039