Table 2.
Comparison of laboratory data between virus negative and re-positive COVID-19 patients after discharge.
| Variables | Normal reference | Day on admission |
Day on discharge |
||||
|---|---|---|---|---|---|---|---|
| negative (n = 132) | re-positive (n = 13) | p value | negative (n = 119) | re-positive (n = 13) | p value | ||
| WBC (109/L) | 3.5–9.5 | 5.4 (2.6–23.6) | 5.7 (3.5–10.0) | 0.626 | 5.8 (3.1–14.4) | 4.9 (3.7–8.1) | 0.375 |
| Neutrophil (109/L) | 1.8–6.3 | 3.5 (1.2–22.2) | 3.6 (1.8–7.5) | 0.468 | 3.3 (1.5–11.6) | 3.1 (2.5–5.8) | 0.745 |
| Lymphocyte (109/L) | 1.1–3.2 | 1.2 (0.3–3.0) | 1.3 (0.3–2.4) | 0.770 | 1.5 (0.6–3.5) | 1.4 (0.7–2.7) | 0.154 |
| CD3 + T cell (per μL) | 770–2041 | 620.1 (136.9–2012.3) | 554.9 (110.9–1249.3) | 0.316 | 1007.4 (377.2–2081.5) | 1181.7 (696.2–1313.7) | 0.568 |
| CD4 + T cell (per μL) | 414–1123 | 344.0 (85.54–1236.4) | 354.5 (68.3–828.1) | 0.437 | 521.3 (199.3–1348.5) | 609.8 (386.6–779.5) | 0.485 |
| CD8 + T cell (per μL) | 238–874 | 255.7 (41.2–805.83) | 195.3 (42.5–426.4) | 0.151 | 433.6 (150.6–982.6) | 421.6 (290.8–572.5) | 0.933 |
| CD19 + B cell (per μL) | 90–560 | 136.6 (28.45–551.85) | 89.7 (28.5–267.7) | 0.186 | 160.0 (48.1- −495.0) | 132.2 (44.7–291.2) | 0.672 |
| CD56 + NK cell (per μL) | 150–1100 | 199.8 (43.57–770.82) | 166.8 (62.7–351.9) | 0.356 | 223.1 (68.1–655.6) | 249.6 (165.9–438.1) | 0.553 |
| Mononuclear (109/L) | 0.1–0.6 | 0.4 (0.1–1.2) | 0.5 (0.2–0.8) | 0.100 | 0.50 (0.20–1.30) | 0.50 (0.20–0.80) | 0.797 |
| Eosinophil (109/L) | 0.02–0.52 | 0.01 (0.0–0.34) | 0.01 (0.0–0.09) | 0.795 | 0.10 (0.0–1.43) | 0.08 (0.04–0.20) | 0.533 |
| Basophil (109/L) | 0.00–0.06 | 0.01 (0.0–0.07) | 0.02 (0.0–0.06) | 0.451 | 0.02 (0.0–0.09) | 0.02 (0.01–0.04) | 0.889 |
| IL-2 (pg/mL) | 1.1–9.8 | 1.35 (0.19–3.27) | 1.07 (0.50–10.31) | 0.519 | 1.36(0.29–2.81) | 1.23 (0.49–2.10) | 0.442 |
| IL-4 (pg/mL) | 0.1–3.0 | 1.52 (0.10–8.53) | 1.26 (0.50–3.12) | 0.226 | 1.62 (0.13–11.71) | 1.87 (0.30–3.09) | 0.387 |
| IL-6 (pg/mL) | 1.7–16.6 | 8.03 (0.78–413.63) | 12.48 (1.36–22.16) | 0.963 | 3.35 (1.08–347.81) | 3.73 (1.85–23.1) | 0.135 |
| IL-10 (pg/mL) | 2.6–4.9 | 3.57 (0.61–39.53) | 3.71 (0.19–24.13) | 0.883 | 2.64 (0.57–7.19) | 3.30 (1.00–5.68) | 0.181 |
| TNF-α (pg/mL) | 0.1–5.2 | 1.25 (0.09–5.32) | 0.69 (0.0–2.55) | 0.051 | 1.00 (0.22–4.97) | 0.920 (0.015–1.64) | 0.191 |
| IFN-γ (pg/mL) | 1.6–17.3 | 1.95 (0.18–178.86) | 1.39 (0.30–12.88) | 0.535 | 1.59 (0.18–178.66) | 1.35 (0.15–2.66) | 0.406 |
| IgG (g/L) | 7.0–16.0 | 12.72 (7.73–28.51) | 10.73 (7.80–18.67) | 0.020 | 12.29 (9.50–15.47) | / | / |
| IgA (g/L) | 0.70–4.0 | 2.37 (0.57–5.26) | 2.12 (0.79–3.61) | 0.194 | 2.34 (1.12–5.31) | / | / |
| IgM (g/L) | 0.40–2.30 | 1.02 (0.38–4.41) | 0.95 (0.33–1.71) | 0.531 | 1.12 (0.74–2.30) | / | / |
| CRP (mg/L) | <0.5 | 10.20 (0.10–185.0) | 5.10 (0.20–65.10) | 0.243 | 1.90 (0.20–66.6) | / | / |
| LDH | 80–285 | 207.0 (110.0–927.0) | 186.0 (137.0–627.0) | 0.958 | 162.0 (110.0–310.0) | 150.0 (136.0–158.0) | 0.299 |
| D-dimer | 0.00–0.55 | 0.24 (0.04–4.38) | 0.33 (0.15–12.98) | 0.680 | 0.54 (0.17–2.07) | / | |
| Alanine aminotransferase (U/L) | 7–40 | 20.0 (5.0–152.0) | 22.0 (10.0–106.0) | 0.890 | 26.0 (6.0–121.0) | 18.5 (11.0–85.0) | 0.548 |
| Aspartate aminotransferase (U/L) | 13–35 | 24.0 (11.0–77.0) | 26.0 (13.0–115.0) | 0.878 | 22.0 (12.0–68.0) | 21.5 (13.0–47.0) | 0.996 |
| Alkaline phosphatase (U/L) | 35–100 | 71.0 (35.0–376.0) | 69.0 (40.0–100.0) | 0.560 | 74.0 (40.0–356.0) | 68.5 (40.0–93.0) | 0.275 |
| gamma-glutamyltransferase (U/L) | 7–45 | 24.0 (10.0–132.0) | 19.0 (11.0–76.0) | 0.409 | 33.0 (12.0–293.0) | 25.0 (11.0–57.0) | 0.075 |
| Total bilirubin (mmol/L) | 5.0–21.0 | 12.75 (3.4–36.5) | 11.9 (5.30–32.7) | 0.906 | 11.4 (4.0–88.0) | 13.7 (4.30–52.7) | 0.126 |