Table 2.
. Laboratory characteristics of study population.
| All patients (n = 320) | Low IL-6/LY group (n = 207) | High IL-6/LY group (n = 113) | P | |
|---|---|---|---|---|
| Blood routine index | ||||
| WBC, 109/L | 7.56 ± 0.27 | 5.99 ± 0.25 | 10.44 ± 0.53 | <0.001 |
| Neutrophil%, % | 75.95 ± 0.84 | 70.31 ± 1.04 | 86.30 ± 0.74 | <0.001 |
| Neutrophil, 109/L | 6.22 ± 0.28 | 4.55 ± 0.25 | 9.28 ± 0.52 | <0.001 |
| Lymphocyte%, % | 16.12 ± 0.64 | 20.44 ± 0.79 | 8.21 ± 0.56 | <0.001 |
| Lymphocyte, 109/L | 0.90 ± 0.04 | 1.04 ± 0.06 | 0.65 ± 0.03 | <0.001 |
| Monocyte%, % | 6.88 ± 0.22 | 7.83 ± 0.29 | 5.14 ± 0.29 | 0.252 |
| Monocyte, 109/L | 0.45 ± 0.02 | 0.43 ± 0.02 | 0.47 ± 0.03 | <0.001 |
| Hemoglobin, mg/dL | 124.73 ± 1.34 | 124.91 ± 1.59 | 124.41 ± 2.46 | 0.931 |
| Platelet, 109/L | 193.25 ± 5.09 | 204.74 ± 6.33 | 172.22 ± 8.23 | <0.001 |
| Coagulation function | ||||
| PT, sec | 15.34 ± 0.34 | 14.48 ± 0.21 | 16.95 ± 0.86 | <0.001 |
| APTT, sec | 42.29 ± 0.76 | 41.43 ± 0.60 | 43.57 ± 1.65 | 0.133 |
| D-dimer, ug/mL FEU | 4.85 ± 0.42 | 2.98 ± 0.40 | 8.39 ± 0.84 | <0.001 |
| Biochemical indexes | ||||
| CTnI, pg/ml | 616.36 ± 199.58 | 168.54 ± 97.51 | 1331.94 ± 487.36 | <0.001 |
| NT-proBNP, pg/ml | 2467.98 ± 521.93 | 1449.30 ± 531.33 | 4022.81 ± 1023.28 | <0.001 |
| ALT, u/L | 37.37 ± 3.56 | 31.75 ± 3.78 | 47.57 ± 7.21 | <0.001 |
| AST (u/L) | 48.30 ± 5.41 | 33.43 ± 1.91 | 75.27 ± 14.53 | <0.001 |
| Albumin, g/L | 33.30 ± 0.30 | 34.83 ± 0.33 | 30.51 ± 0.50 | <0.001 |
| Globulin, g/L | 34.17 ± 0.36 | 33.41 ± 0.45 | 35.56 ± 0.58 | <0.001 |
| TC, mmol/l | 3.57 ± 0.05 | 3.66 ± 0.06 | 3.42 ± 0.08 | 0.008 |
| TG, mmol/L | 1.64 ± 0.07 | 1.51 ± 0.09 | 1.80 ± 0.12 | 0.001 |
| HDL-C, mmol/l | 0.85 ± 0.02 | 0.95 ± 0.03 | 0.75 ± 0.03 | <0.001 |
| LDL-C, mmol/l | 2.18 ± 0.06 | 2.30 ± 0.07 | 2.05 ± 0.11 | 0.014 |
| CK, u/L | 254.18 ± 37.96 | 147.14 ± 18.86 | 382.39 ± 78.34 | <0.001 |
| LDH, u/L | 427.50 ± 16.44 | 334.58 ± 13.65 | 597.58 ± 33.86 | <0.001 |
| Urea, mmol/L | 7.72 ± 0.45 | 5.62 ± 0.31 | 11.55 ± 1.04 | <0.001 |
| Creatinine, mmol/L | 95.75 ± 5.04 | 89.05 ± 6.76 | 107.96 ± 6.98 | <0.001 |
| Immuno-inflammatory indices | ||||
| Hs-CRP, mg/L | 76.95 ± 4.01 | 52.85 ± 3.93 | 119.18 ± 7.05 | <0.001 |
| ESR, mm/H | 38.93 ± 1.58 | 35.39 ± 1.85 | 45.02 ± 2.78 | 0.003 |
| Ferritin, ug/L | 1483.87 ± 188.08 | 854.89 ± 87.86 | 2366.85 ± 421.14 | <0.001 |
| PCT, ng/mL | 1.41 ± 0.48 | 0.23 ± 0.05 | 3.44 ± 1.28 | <0.001 |
| Ig A, g/L | 2.40 ± 0.09 | 2.20 ± 0.10 | 2.61 ± 0.14 | 0.017 |
| Ig G, g/L | 12.43 ± 0.29 | 11.71 ± 0.35 | 13.21 ± 0.47 | 0.010 |
| Ig M, g/L | 1.06 ± 0.04 | 1.09 ± 0.06 | 1.03 ± 0.07 | 0.214 |
| Alexin C3, g/L | 0.83 ± 0.02 | 0.87 ± 0.02 | 0.79 ± 0.03 | 0.007 |
| Alexin C4, g/L | 0.24 ± 0.01 | 0.25 ± 0.01 | 0.22 ± 0.01 | 0.014 |
| IL-1β, pg/ml | 5.93 ± 0.26 | 5.67 ± 0.23 | 6.25 ± 0.51 | 0.890 |
| IL-2R, pg/ml | 1008.15 ± 51.85 | 716.46 ± 59.66 | 1356.64 ± 77.04 | <0.001 |
| IL-6, pg/ml | 113.32 ± 31.35 | 51.18 ± 36.95 | 187.55 ± 52.10 | <0.001 |
| IL-8, pg/ml | 68.94 ± 30.36 | 21.64 ± 3.83 | 125.45 ± 66.25 | <0.001 |
| IL-10, pg/ml | 12.44 ± 1.25 | 7.92 ± 0.67 | 17.83 ± 2.55 | <0.001 |
| TNF-α, pg/ml | 11.70 ± 0.63 | 9.13 ± 0.63 | 14.76 ± 1.10 | <0.001 |
| MuLBSTA score | 7.88 ± 0.21 | 7.46 ± 0.25 | 8.65 ± 0.37 | 0.024 |