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. 2021 Mar 12;34(13):108915. doi: 10.1016/j.celrep.2021.108915

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© 2021 The Author(s)

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Epitope numbers in patients are related with severity

(A and B) The distribution of the numbers of the responsive epitopes in both the COVID-19 (n = 1,004) and control groups (n = 528). For the COVID-19 group, samples collected less than 15 days after symptom onset were excluded.

(C) The numbers of the responsive epitopes in the three groups with regard to severity and outcome.

(D) The S1 IgG signal intensity of the samples with different numbers of the responsive epitopes.

For (B)–(D), the data were presented by mean + SD. p values were calculated using the two-sided t test for others. For (C), the p value was adjusted for multiple comparisons by BH (Benjamini and Hochberg) method.