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. 2021 Feb 2;2021:6652957. doi: 10.1155/2021/6652957

Table 2.

Prevalence of clinical features segregated into categories according to the literature.

Clinical features n (%)
Primary criteria 58 (100)
Hypertelorism 55 (94.8)
Short stature 48 (82.8)
Shawl scrotum 46 (79.3)
Anteverted nostrils/short nose 44 (75.9)
Brachydactyly/wide fingers 36 (62.1)
Clinodactyly 25 (43.1)
Short/broad hands 23 (39.7)
Interdigital webbing 20 (34.5)
Camptodactyly 19 (32.8)
Syndactyly 14 (24.1)
Bottom lip fold 3 (5.2)

Secondary criteria
Ptosis 34 (58.6)
Cryptorchidism 29 (50.0)
Joint hypermobility 29 (50.0)
Widow's peak 27 (46.6)
Dysplastic ears 24 (41.4)
Downward slanting palpebral fissures 23 (39.7)
Inguinal hernia 21 (36.2)
Wide feet 18 (31.0)
Umbilical hernia 9 (15.5)
Prominent umbilicus 4 (6.9)

Additional criteria
Long philtrum 32 (55.2)
Simian creases 20 (34.5)
Frontal bossing 16 (27.6)
Midface hypoplasia 12 (20.7)
Developmental delay 10 (17.2)
Bone age retarded 7 (12.1)
Obesity 6 (10.3)
Dental malocclusion 3 (5.2)
Hypospadias 1 (1.7)

Others
Metatarsus varus 13 (22.4)
Crease below the lower lip 11 (19.0)
Low set ears 11 (19.0)
Round face 10 (17.2)
Interphalangeal joint contracture 9 (15.5)
Ogival palatus 9 (15.5)
Pectus excavatum 8 (13.8)
Broad nasal ridge 7 (12.1)
Micrognathia 7 (12.1)
Short neck 7 (12.1)
ADHD 6 (10.3)