Table 1.
Distribution of [125I]I-pHLIP (Var7) in MDA-MB-231 tumor-bearing nude mice (%ID/g, n = 3).
| Organs | Time (h) | ||||
|---|---|---|---|---|---|
| 0.5 | 1 | 2 | 4 | 8 | |
| Heart | 4.1 ± 0.5 | 3.9 ± 0.7 | 2.0 ± 0.4 | 1.1 ± 1.1 | 0.5 ± 0.3 |
| Liver | 13.9 ± 2.7 | 8.0 ± 1.9 | 4.0 ± 0.6 | 1.8 ± 0.2 | 0.7 ± 0.2 |
| Spleen | 3.0 ± 1.1 | 3.0 ± 0.6 | 1.4 ± 0.4 | 0.7 ± 0.2 | 0.3 ± 0.1 |
| Lung | 3.4 ± 1.2 | 2.5 ± 1.0 | 1.2 ± 0.5 | 0.5 ± 0.3 | 0.2 ± 0.1 |
| Kidney | 4.2 ± 0.6 | 5.1 ± 1.1 | 2.3 ± 0.8 | 1.2 ± 0.4 | 0.5 ± 0.2 |
| Pancreas | 3.3 ± 0.8 | 4.1 ± 1.2 | 2.1 ± 0.6 | 0.9 ± 0.3 | 0.3 ± 0.1 |
| Stomach | 4.7 ± 1.2 | 5.1 ± 1.2 | 4.3 ± 1.0 | 2.2 ± 0.8 | 0.7 ± 0.2 |
| Small intestine | 3.3 ± 1.5 | 4.2 ± 0.6 | 2.8 ± 1.0 | 1.3 ± 0.5 | 0.4 ± 0.1 |
| Bladder | 3.8 ± 1.1 | 4.3 ± 1.1 | 2.1 ± 0.9 | 1.0 ± 0.6 | 0.5 ± 0.2 |
| Thyroid | 4.3 ± 1.7 | 5.6 ± 1.4 | 3.4 ± 1.0 | 1.6 ± 0.8 | 0.8 ± 0.4 |
| Brain | 0.6 ± 0.1 | 0.5 ± 0.1 | 0.3 ± 0.1 | 0.1 ± 0.1 | 0.1 ± 0.1 |
| Bone | 2.9 ± 0.3 | 2.8 ± 0.1 | 1.5 ± 0.5 | 0.7 ± 0.2 | 0.2 ± 0.1 |
| Muscle | 1.7 ± 0.6 | 1.4 ± 0.8 | 0.6 ± 0.2 | 0.2 ± 0.1 | 0.1 ± 0.1 |
| Blood | 12.0 ± 1.5 | 6.5 ± 1.5 | 2.8 ± 0.6 | 1.2 ± 0.5 | 0.5 ± 0.1 |
| Tumor | 3.6 ± 0.5 | 6.9 ± 0.4 | 3.6 ± 0.7 | 2.0 ± 0.6 | 1.0 ± 0.4 |