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. 2021 Feb 4;8(3):ofab055. doi: 10.1093/ofid/ofab055

Table 4.

Features of Prosthetic Valve IE Due to Corynebacteria Compared With Other Pathogens

Demographics Corynebacteria Staphylococcus aureus Non-BHS Enterococcus faecalis
n = 21 n = 279 n = 385 n = 201
Definite IE (%) 86 86 78 78
Age (years, median) 71 (60–77)a 66 (56–81)a 70 (62–82)a 73 (67–81)a
Gender (%male) 81 72 72 78
Underlying disease (%)
 Diabetes 24 16 16 23
 Cancerb 9 13 14 21
 IVDU 0 10 4 8
Underlying Heart Disease (%)
 Native valve disease 24 15 18 14
Previous IE 24 22 17 22
Pacemaker/ICD 33 25 14* 19
Type of Infection (%)
 Aortic valve 70 56 53 56
 Mitral valve 14 23 19 24
 Nosocomial 19 15 4 15
Course of Disease
 Onset to hospitalization (days) 8 2**** 9 7
 Length of stay (days) 43 (33–46)a 39 (27–50)a 33** (28–43)a 42 (27–46)a
 Treatment length (days) 38 (29–47)a 38 (28–43)a 33 (28–42)a 42 (30–43)a
Embolization (%) 10 35* 16 20
Onset of symptoms to operation (days) 19 (10–35)a 15 (9–28)a 40** (21–53)a 39* (15–66)a
Onset of admission to operation (days) 8 (4–17)a 13 (8–25)a 15* (9–28)a 15* (9–34)a
Surgery (%)c 57 32* 17**** 15****
Mortality (%)d 5 25* 7 11

Abbreviations: ICD, intracardiac device; IE, infective endocarditis; IVDU, intravenous drug use; non-BHS, non-beta-hemolytic streptococci; NVE, native valve endocarditis; PME, pacemaker endocarditis; PVE, prosthetic valve endocarditis.

aInterquartile range.

bMalignancy with treatment during the past 5 years.

cSurgery during treatment.

dIn-hospital mortality. Continuous data are presented as median and categorical variables as count (percentage). The P values for difference between characteristics of patients with IE caused by corynebacteria compared with patients with S aureus, non-BHS streptococci, or E faecalis, respectively, are indicated as follows:

*, P < .05.

**, P < .01.

***, P < .001.

****, P < .0001.