Table 4.
Demographics | Corynebacteria | Staphylococcus aureus | Non-BHS | Enterococcus faecalis |
---|---|---|---|---|
n = 21 | n = 279 | n = 385 | n = 201 | |
Definite IE (%) | 86 | 86 | 78 | 78 |
Age (years, median) | 71 (60–77)a | 66 (56–81)a | 70 (62–82)a | 73 (67–81)a |
Gender (%male) | 81 | 72 | 72 | 78 |
Underlying disease (%) | ||||
Diabetes | 24 | 16 | 16 | 23 |
Cancerb | 9 | 13 | 14 | 21 |
IVDU | 0 | 10 | 4 | 8 |
Underlying Heart Disease (%) | ||||
Native valve disease | 24 | 15 | 18 | 14 |
Previous IE | 24 | 22 | 17 | 22 |
Pacemaker/ICD | 33 | 25 | 14* | 19 |
Type of Infection (%) | ||||
Aortic valve | 70 | 56 | 53 | 56 |
Mitral valve | 14 | 23 | 19 | 24 |
Nosocomial | 19 | 15 | 4 | 15 |
Course of Disease | ||||
Onset to hospitalization (days) | 8 | 2**** | 9 | 7 |
Length of stay (days) | 43 (33–46)a | 39 (27–50)a | 33** (28–43)a | 42 (27–46)a |
Treatment length (days) | 38 (29–47)a | 38 (28–43)a | 33 (28–42)a | 42 (30–43)a |
Embolization (%) | 10 | 35* | 16 | 20 |
Onset of symptoms to operation (days) | 19 (10–35)a | 15 (9–28)a | 40** (21–53)a | 39* (15–66)a |
Onset of admission to operation (days) | 8 (4–17)a | 13 (8–25)a | 15* (9–28)a | 15* (9–34)a |
Surgery (%)c | 57 | 32* | 17**** | 15**** |
Mortality (%)d | 5 | 25* | 7 | 11 |
Abbreviations: ICD, intracardiac device; IE, infective endocarditis; IVDU, intravenous drug use; non-BHS, non-beta-hemolytic streptococci; NVE, native valve endocarditis; PME, pacemaker endocarditis; PVE, prosthetic valve endocarditis.
aInterquartile range.
bMalignancy with treatment during the past 5 years.
cSurgery during treatment.
dIn-hospital mortality. Continuous data are presented as median and categorical variables as count (percentage). The P values for difference between characteristics of patients with IE caused by corynebacteria compared with patients with S aureus, non-BHS streptococci, or E faecalis, respectively, are indicated as follows:
*, P < .05.
**, P < .01.
***, P < .001.
****, P < .0001.