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. 2021 Mar 11;16:20. doi: 10.1186/s13000-021-01079-2

Table 2.

List of morphological features of primary and metastatic ovarian carcinomas

Favor primary Favor metastatic Unhelpful features
smooth capsule involvement of surface and superficial cortex gross cysts
evenly distributed cystic and solid areas (no discrete nodularity) nodular pattern (gross and/or microscopic) including gross mucinous multinodular appearance gross solid, papillary, hemorrhagic areas
areas of MBT and/or mucinous cystadenoma areas of MBT and/or mucinous cystadenoma less frequent, commonly associated with high grade nuclear atypia nature of the content of the cysts
expansile invasion infiltrative (destructive) invasion pseudomyxoma ovarii
complex papillary pattern bilaterality cribriform, villous, or solid growth
size > 10 cm (>  15 cm) hilar involvement goblet cells
associated teratoma or Brenner tumor single cell invasion tumor grade
microscopic cystic glands signet ring cells focal areas resembling colonic carcinoma
vascular invasion
mural nodule microscopic mucus on the surface
unilateral pseudomyxoma peritonei
low stage intraperitoneal spread
low age colloid morphology
established history of cancer

MBT mucinous borderline tumor