Fig. 1.

SOCS6 expression is correlated with prognosis of ESCC patients and radiosensitivity of ESCC cells. a, b Effects of SOCS6 expression on survival of 57 ESCC patients (red: SOCS6 high; blue: SOCS6 low); c, d ESCC cells were transfected with lentivirus expressing the SOCS6 protein, and SOCS6 expression was validated by WB analysis (n = 3); e–g cells overexpressing SOCS6 were treated with 0, 2, 4, 6, or 8 Gy of 4 MV X-rays (n = 3). Cells were stained and counted after 14 days of culture. The survival curves are shown on the left. The data are presented as mean ± SD, *P < 0.05, **P < 0.01 and ***P < 0.001