Table 5.
DED Questionnaires in the Pre- and Post-Index Periods
| Pre-Index n=600 | 3-Months (± 30 Days) Post-Index n=571 | 6-Months (± 30 Days) Post-Index n=534 | 12-Months (± 60 Days) Post-Index n=320 | |
|---|---|---|---|---|
| 5-Item Dry Eye Questionnaire (DEQ-5) score [0–22] | ||||
| Patients with documentation of symptom score, n (% [95% CI]) | 77 (12.8 [10.3, 15.8]) | 10 (1.8 [0.8, 3.2]) | 12 (2.2 [1.2, 3.9]) | 14 (4.4 [2.4, 7.2]) |
| Mean ± SD [median] (95% CI of mean) | 14.3 ± 4.2 [15.0] (13.3, 15.2) | 9.8 ± 5.8 [9.0] (5.7, 13.9) | 7.4 ± 4.8 [6.0] (4.4, 10.4) | 6.5 ± 4.2 [6.0] (4.1, 8.9) |
| Ocular Surface Disease Index (OSDI) score [0–100] | ||||
| Patients with documentation of symptom score, n (% [95% CI]) | 54 (9.0 [6.8, 11.6]) | 6 (1.1 [0.4, 2.3]) | 6 (1.1 [0.4, 2.4]) | 8 (2.5 [1.1, 4.9]) |
| Mean ± SD [median] (95% CI of mean) | 60.5 ± 24.8 [65.5] (53.8, 67.3) | 31.3 ± 17.8 [25.0] (12.6, 50.0) | 41.8 ± 23.7 [35.0] (17.0, 66.7) | 28.8 ± 17.3 [25.0] (14.3, 43.2) |
| Standardized Patient Evaluation of Eye Dryness (SPEED) questionnaire score [0–28] | ||||
| Patients with documentation of symptom score, n (% [95% CI]) | 37 (6.2 [4.4, 8.4]) | 5 (0.9 [0.3, 2.0]) | 4 (0.7 [0.2, 1.9]) | 7 (2.2 [0.9, 4.5]) |
| Mean ± SD [median] (95% CI of mean) | 17.5 ± 5.4 [20.0] (15.7, 19.3) | 12.2 ± 3.3 [12.0] (8.0, 16.4) | 6.8 ± 3.3 [7.0] (1.5, 12.0) | 7.7 ± 5.0 [5.0] (3.1, 12.4) |
| No symptom questionnaire reported, n (% [95% CI]) | 383 (63.8 [59.8, 67.7]) | 539 (94.4 [92.2, 96.1]) | 497 (93.1 [90.6, 95.1]) | 281 (87.8 [83.7, 91.2]) |
Abbreviations: CI, confidence interval; DED, dry eye disease; SD, standard deviation.