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Pharmacokinetic (PK) analysis of 6BN in guinea pigs. (A) Bioavailability curves for 6BN in non-pregnant female adult guinea pigs using plasma multi-sampling. The PK time course is shown for oral delivery compared to IV. (B) PK time course of 6BN in plasma and brain (dose 40 mg/kg, p.o.). Note y-axis is log scale, in (B) only. Error bars ±SEM.
