TABLE 3.

PK analysis of 6BN in fetal and maternal plasma and brain.

Parameters	Unit	Mom		Fetus
		Plasma	Brain	Plasma	Brain
T1/2	hr	2.74	11.5	3.29	6.11
Cmax	ng/mL	2,250 (±1,310)	204 (±73)	412 (±120)	310 (±77)
Tmax	hr	1	0.25	1	0.25
AUClast	hr*ng/mL	3,810 (±1,022)	1,060 (±179)	1,190 (±96.1)	1,360 (±101)
AUCinf	hr*ng/mL	4,090	3,040	1,430	2,440
AUCO-4	hr*ng/mL	3,330	606	910	891

Values are from same data shown in Figure 1B.