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Effect of methadone on pup birthweight.
| MTD dose (mg/kg) | Number of pups (n) | Number of litters | Birthweight (g) |
|---|---|---|---|
| 2 | 6 | 2 | 95.7 ± 7.1 a |
| 5 | 41 | 7 | 75.4 ± 1.8 |
| 7 | 8 | 2 | 72.4 ± 4.3 |
| 10 | 11 | 3 | 78.4 ± 4.0 |
| 0 (saline ctl) | 28 | 5 | 75.5 ± 3.1 |
All values ± SEM. No significant overall effect of MTD by ANOVA: F (4,89) = 1.8671, p = 0.1232. ap < 0.05, for comparison to saline control, by Dunnetts posthoc test.
