Table 5.
Estimates of Log Hazard Ratios, With Standard Error Estimates in Parentheses, from the Proportional Hazards Regression Analysis of the National Wilms’ Tumor Study
| Histological assessment | Tumor stage | ||||||
|---|---|---|---|---|---|---|---|
| n2 | Design | Central | Local | II | III | IV | Age |
| 400 | CC | 1.573 (0.359) | 0.114 (0.291) | 0.682 (0.125) | 0.793 (0.125) | 1.067 (0.141) | 0.078 (0.015) |
| SCC | 1.579 (0.322) | 0.068 (0.297) | 0.677 (0.127) | 0.790 (0.127) | 1.092 (0.143) | 0.078 (0.015) | |
| ODS | 1.882 (0.382) | −0.127 (0.302) | 0.692 (0.127) | 0.795 (0.128) | 1.083 (0.145) | 0.080 (0.015) | |
| YDS | 2.210 (0.269) | −0.034 (0.229) | 0.704 (0.129) | 0.835 (0.130) | 1.113 (0.147) | 0.080 (0.015) | |
| OPT | 1.549 (0.260) | 0161 (0.258) | 0.666 (0.124) | 0.781 (0.123) | 1.151 (0.139) | 0.077 (0.015) | |
| 1142 | CC | 1.513 (0.219) | 0.128 (0.199) | 0.676 (0.131) | 0.789 (0.131) | 1.062 (0.146) | 0.077 (0.015) |
| SCC | 1.578 (0.193) | 0.083 (0.195) | 0.665 (0.113) | 0.788 (0.112) | 1.134 (0.132) | 0.077 (0.015) | |
| NCC | 1.510 (0.226) | 0.133 (0.198) | 0.675 (0.132) | 0.789 (0.132) | 1.063 (0.147) | 0.077 (0.015) | |
| CM | 1.585 (0.192) | 0.077 (0.200) | 0.666 (0.117) | 0.789 (0.117) | 1.134 (0.159) | 0.077 (0.016) | |
| YDS | 1.947 (0.202) | −0.109 (0.184) | 0.699 (0.124) | 0.838 (0.124) | 1.110 (0.140) | 0.072 (0.015) | |
| OPT | 1.424 (0.185) | 0.228 (0.181) | 0.667 (0.111) | 0.777 (0.111) | 1.135 (0.141) | 0.075 (0.015) | |
| 4028 | FC | 1.444 (0.135) | 0.203 (0.144) | 0.662 (0.122) | 0.802 (0.121) | 1.137 (0.135) | 0.071 (0.015) |
NOTE: CC, SCC, ODS, YDS, OPT, NCC, CM, and FC denote case-cohort sampling, stratified case-cohort sampling, general failure-time outcome-dependent sampling, Y-dependent sampling, optimal design, nested case-control sampling, counter-matching, and full-cohort, respectively. Estimates of log hazard ratios and standard errors under the CC, SCC, ODS, NCC, and CM designs are averaged over 1000 replicates.