Table 1. Baseline characteristic of dementia patients and age-sex matched control group.
| Dementia (N = 6,028) | Controls (N = 30,140) | P-value | |
|---|---|---|---|
| Female sex, n (%) | 4,221 (70.0) | 21,105 (70.0) | 1.000 |
| Age group, n (%) | |||
| 20–39 years | 4 (0.1) | 20 (0.1) | 1.000 |
| 40–64 years | 459 (7.6) | 2,295 (7.6) | |
| ≥65 years | 5,565 (92.3) | 27,825 (92.3) | |
| AD, n (%) | 5,045 (83.6) | - | |
| VaD, n (%) | 734 (12.2) | - | |
| Residence city size, n (%) | |||
| Seoul, metropolitan | 1,053 (17.5) | 5,319 (17.7) | 0.459 |
| Large cities* | 1,420 (23.5) | 6,877 (22.8) | |
| Other areas | 3,555 (59.0) | 17,944 (59.5) | |
| Household income**, n (%) | |||
| High (>20%) | 4,613 (76.5) | 22,359 (74.2) | <0.001 |
| Low (≤20%) | 1,415 (23.5) | 7,781 (25.8) | |
| Comorbidity, n (%) | |||
| Hypertension | 410 (67.1) | 27,772 (61.2) | 0.003 |
| Diabetes | 178 (29.1) | 9,780 (26.7) | 0.171 |
| Dyslipidemia | 98 (16.0) | 4,744 (13.3) | 0.052 |
| Mood disorder | 905 (8.0) | 2,420 (15.0) | <0.001 |
| Charlson Comorbidity Index, n (%) | |||
| 0 | 50 (0.8) | 3,723 (12.4) | <0.001 |
| 1 | 559 (9.3) | 6,635 (22.0) | |
| 2 | 1,170 (19.4) | 6,657 (22.1) | |
| ≥3 | 4,249 (70.5) | 13,125 (43.6) |
AD, Alzheimer’s disease; VaD, vascular dementia
*Large City: Busan, Daegu, Gwangju, Incheon, Daejeon, Ulsan
**Household income (divided into five quintiles and described in terms of the highest and lowest 20%).