Table 1. Description of patients with critical subarachnoid hemorrhage requiring mechanical ventilation.
Variables comparison between the good- and poor-outcome groups.
| Variable | Overall (N = 229) | Good-Outcome (N = 73) | Poor-Outcome (N = 176) | Difference (95% CI) |
|---|---|---|---|---|
| Age, years | 55 ± 13 | 51.70 ±13.53 | 56.48 ± 12.57 | 4.78 (1.15; 8.41) |
| Male sex, n (%) | 84 (37%) | 22 (30.14%) | 62 (39.74%) | 9.61 (-3.42; 22.64) |
| Tobacco use, n (% | 75 (33%) | 30 (41.10%) | 45 (28.85%) | -12.25 (-25.59; 1.09) |
| GCS on admission | ||||
| ≤5 | 88 (42%) | 21 (32.81%) | 67 (46.53%) | 13.72 (-0.38; 27.81) |
| 6–8 | 69 (33%) | 19 (29.69%) | 50 (34.72%) | 5.03 (-8.59; 18.66) |
| ≥9 | 51 (25%) | 24 (37.50%) | 27 (18.75%) | -18.75 (-32.22; -5.28) |
| SAPSII on admission | 42.3 ± 12 | 37.80 ± 10.38 | 44.46 ± 12.45 | 6.67 (3.39; 9.94) |
| WFNS score, n (%) | ||||
| III | 21 (9%) | 11 (15.07%) | 10 (6.41%) | -8.66 (-17.72; 0.40) |
| IV | 94 (41%) | 34 (46.58%) | 60 (38.46%) | -8.11 (-21.87; 5.64) |
| V | 114 (50%) | 28 (38.36%) | 86 (55.13%) | 16.77 (3.16; 30.39) |
| Intracerebral hemorrhage, n (%) | 105 (46%) | 28 (38.36%) | 77 (49.36%) | 11.00 (-2.63; 24.64) |
| Fisher Score, n (%) | ||||
| I | 1 | 1 (1.37%) | 0 | -1.37 (-4.04; 1.30) |
| II | 5 (2%) | 3 (4.11%) | 2 (1.28%) | -2.83 (-7.71; 2.06) |
| III | 43 (19%) | 16 (21.92%) | 27 (17.31%) | -4.61 (-15.80; 6.58) |
| IV | 180 (79%) | 53 (72.60%) | 127 (81.41%) | 8.81 (-3.11; 20.72) |
| Hydrocephalus requiring EVD, n (%) | 156 (68%) | 46 (63.01%) | 110 (70.51%) | 7.50 (-5.69; 20.68) |
| Aneurysm-securing procedure, n (%) | ||||
| Coiling | 145 (63%) | 54 (73.97%) | 91 (58.33%) | -15.64 (-28.33; -2.94) |
| Clipping | 60 (26%) | 18 (24.66%) | 42 (26.92%) | -15.64 (-28.33; -2.94) |
| Both | 4 (2%) | 1 (1.37%) | 3 (1.92%) | -15.64 (-28.33; -2.94) |
| No treatment (Failure/Withdrawal of care) | 20 (9%) | 0 | 20 (12.82%) | 12.82 (7.57; 18.07) |
| Aneurysm-securing delay, n (%) | ||||
| <12 hours | 129 (56%) | 43 (58.90%) | 86 (55.13%) | -3.78 (-17.50; 9.95) |
| 12 h–24 hours | 65 (28%) | 26 (35.62%) | 39 (25.00%) | -10.62 (-23.53; 2.30) |
| 24–48 hours | 9 (4%) | 2 (2.74%) | 7 (4.49%) | 1.75 (-3.21; 6.70) |
| >48 hours | 6 (3%) | 2 (2.74%) | 4 (2.56%) | -0.18 (-4.67; 4.32) |
| Failure | 7 (3%) | 0 | 7 (4.49%) | -0.18 (-4.67; 4.32) |
| Withdrawal of care | 13 (6%) | 0 | 13 (8.33%) | 8.33 (4.00; 12.67) |
| Early brain injuries, n (%) | 163 (71%) | 36 (49.32%) | 127 (81.94%) | 32.62 (19.65; 45.59) |
| Rebleeding, n (%) | 33 (14%) | 2 (2.74%) | 31 (19.87%) | 17.13 (9.84; 24.43) |
| Angiographic vasospasm, n (%) | 80 (35%) | 22 (30.14%) | 58 (37.18%) | 7.04 (-5.93; 20.02) |
| Delayed cerebral ischemia, n (%) | 63 (27%) | 14 (19.18%) | 49 (31.41%) | 12.23 (0.63; 23.83) |
| Delay of mRS assessment, months | 24 ± 25 | 41.20 ± 22.25 | 16.34 ± 23.04 | -24.86 (-31.60;-18.12) |
Description of the 229 patients with critical aneurysmal subarachnoid hemorrhage. Comparison of variables between the good- and poor-outcome groups (multivariable analysis). Data are expressed as the means ± SD. aSAH indicates Aneurysmal Subarachnoid Hemorrhage; GCS, Glasgow Coma Scale; SAPSII, Simplified Acute Physiology Score II; WFNS, World Federation of Neurological Surgeons; EVD, External Ventricular Drain; mRS, modified Rankin Score; ICU, Intensive Care Unit.