Skip to main content
. 2021 Mar 12;16(3):e0240074. doi: 10.1371/journal.pone.0240074

Fig 4. Effect of cholinergic antagonists on CA3-CA1 synchronous epileptiform discharges induced in synaptic blockers aCSF.

Fig 4

(A) Application of atropine does not block CA3-CA1 synchronous discharges: (1) burst of discharges in synaptic blockers aCSF, (2) synchronous epileptiform discharges appear during atropine application. (B) Application of d-tubocurarine blocks CA3-CA1 synchronous epileptiform discharges: (3) burst of discharges in synaptic blockers aCSF, (4) reduction of the discharges after tubocurarine application, (5) epileptiform discharges decrease under tubocurarine application.