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. 2021 Mar 12;16(3):e0240074. doi: 10.1371/journal.pone.0240074

Fig 6. Effect of selective nicotinic antagonists on spontaneous epileptiform discharges in synaptic blockers aCSF.

Fig 6

(A) Application of α7 nAChRs antagonist MLA (100 nM) does not stop synchronous discharges: (1) burst of discharges in synaptic blockers aCSF; (2) burst of discharges during MLA application; (3) single field discharges in presence of MLA and (4) after wash out. (B) Synchronous burst of discharges appears in (1) synaptic blockers aCSF, (2) after DhβE application, and after perfusion was returned to synaptic blockers aCSF (3). (C) Summary data of the effect of cholinergic antagonists on cross-correlation between CA3 and CA1 field potential in synaptic blockers aCSF.