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. 2021 Mar 12;16(3):e0240074. doi: 10.1371/journal.pone.0240074

Table 1. Effect of cholinergic antagonists on CA3-CA1 synchronization of epileptiform discharges.

Cholinergic antagonist Cross-correlation control Cross-correlation application Statistical significance (Wilcoxon signed ranks test) Number of slices
atropine, 10 μM 0.56 ± 0.15 0.38 ± 0.19 - p = 0.059 n = 6
d-tubocurarine, 50 μM 0.55 ± 0.25 0.13 ± 0.05 * p = 0.036 n = 6
MLA, 100 nM 0.56 ± 0.08 0.31 ± 0.18 - p = 0.059 n = 5
DhβE, 10 μM 0.48 ± 0.22 0.43 ± 0.33 - p = 0.850 n = 4
MEC, 50 μM 0.45 ± 0.18 0.10 ± 0.09 ** p = 0.002 n = 12