Table 1. Group characteristics of the donors where LCM and transcriptome analysis were successful.
| Children | Adolescents | Young Adults | Middle-aged | Elderly | |
|---|---|---|---|---|---|
| Mean age, years, (range) | 5.8 (1–12) | 15.9 (13–18) | 29.2 (21–35) | 56.3 (50–63) | 75.9 (72–81) |
| Mean HbA1c*, %, (range) | 5.3 (5.2–5.4) | 5.6 (5.4–5.8) | 5.3 (4.8–5.7) | 5.8 (5.4–6.3) | 5.7 (5.5–5.8) |
| Mean HbA1c, mmol/mol, (range) | 34.5 (33–36) | 37.7 (36–40) | 34.4 (29–39) | 40 (36–45) | 39.2 (37–40) |
| Number of donors, n | 5 | 8 | 6 | 8 | 6 |
| Male, n | 5 | 4 | 5 | 4 | 3 |
| Female, n | 0 | 4 | 1 | 4 | 3 |
| Mean BMI, kg/m2, (range) | 16.42 (13.9–20.4) | 22.4 (16–28.9) | 25.1 (21.8–28) | 23.9 (19.4–29) | 24.2 (22.3–26.1) |
| Mean SI, high/low, (range) | n/a | 10.1 | 21.4 (3.9–64.3) | 8.7 (2.3–14.4) | 4.6 (2.0–6.3) |
*HbA1c was available from 4/5 children, 3/8 adolescents, 5/6 young adults, 8/8 middle-aged 6/6 elderly; SI = stimulation index.