Table 3.

Correlation coefficients (R Spearman) between DPP-4 and other biomarkers, clinical indexes (HBI and pMS), Mayo endoscopic score, and immunohistochemical expression in IBD patients

	Parameters	Correlation (r spearman)	P
UC	fDPP-4 vs sDPP-4 (n = 51)	0.52	<0.001
	fDPP-4 vs FC (n = 51)	−0.43	0.001
	fDPP-4 vs CRP (n = 51)	−0.32	0.022
	fDPP-4 vs pMS (n = 51)	−0.51	<0.001
	fDPP-4 vs Mayo endoscopic score (n = 22)	−0.57	0.005
	fDPP-4 vs DPP-4 intestinal expression (n = 13)	0.54	0.049
	sDPP-4 vs DPP-4 intestinal expression (n = 13)	0.72	0.006
Ileal CD	fDPP-4 vs sDPP-4 (n = 30)	−0.18	0.356
	fDPP-4 vs FC (n = 30)	0.32	0.081
	fDPP-4 vs CRP (n = 30)	0.43	0.018
	fDPP-4 vs HBI (n = 30)	0.23	0.228
	fDPP-4 vs DPP-4 intestinal expression (n = 10)	−0.06	0.873
	sDPP-4 vs DPP-4 intestinal expression (n = 12)	0.64	0.025

CD, Crohn's disease; CRP, C-reactive protein; DPP-4, dipeptidyl peptidase-4; FC, fecal calprotectin; fDPP-4, fecal dipeptidyl peptidase-4; HBI, Harvey-Bradshaw index; pMS, partial Mayo Score; sDPP-4, serum dipeptidyl peptidase-4; UC, ulcerative colitis.