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. Author manuscript; available in PMC: 2021 Mar 12.
Published in final edited form as: J Tissue Eng Regen Med. 2020 Dec 1;15(1):24–36. doi: 10.1002/term.3160

FIGURE 2.

FIGURE 2

RT-qPCR was performed on precision templated scaffolds (PTS) resident cells and their small extracellular vesicles (sEVs) isolated from 1 week subcutaneously implanted 40- and 100-μm PTS. Gene targets were the macrophage panel denoted in Table 1. Transcriptional differences between cells and sEVs isolated from 40- and 100-μm pore PTS explanted from LysM-Cre+/0:mT/mG+/0 mice after 1 week detailed differential gene expression in both cells and their sEVs as a function of pore size (*p < 0.05, n = 6 for 40-μm PTS and n = 5 for 100-μm PTS)