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. Author manuscript; available in PMC: 2021 Mar 12.
Published in final edited form as: J Tissue Eng Regen Med. 2020 Dec 1;15(1):24–36. doi: 10.1002/term.3160

FIGURE 4.

FIGURE 4

RT-qPCR performed on EL-4 (immortalized T cell line) cells treated with precision templated scaffolds (PTS) cell-derived small extracellular vesicles (sEVs) from PTS implanted for 1 week. Gene targets were chosen using the T cell panel denoted in Table 1. The transcriptional response of the immortalized T cells exposed to 40- and 100-μm PTS cell-derived sEVs is upregulated compared to the untreated cells, and the 40-μm PTS cell-derived sEV treatment caused differential gene regulation compared to the 100 μm PTS cell-derived sEV treatment (*p < 0.05, n = 4 for sEV treated and 10 for untreated)