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RT-qPCR performed on stimulated murine primary splenic T cells treated with 40- and 100-μm precision templated scaffolds resident cell-derived sEVs for 48 h. Gene regulation of transcripts detailed in Table 1 indicate differential responses as a result of small extracellular vesicles treatment in pore-size-dependent and -independent manners (* < 0.05, n = 5)
