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Proteomic analysis of PPA treated HCT116 cell line. A-B) Volcano plots illustrate significantly differentially expressed protein in 15 μM (A) and 30 μM (B) PPA treated HCT116 cells (fold change: PPA/DMSO). C-D) Venn diagrams of up-regulated protein (C) and down-regulated (D) proteins (p < 0.05) between 15 μM, 30 μM PPA-treated groups and p97 interactors. The log2FC range of 15 μM is −5.56 to −0.26 and 0.26 to 3.24 and the log2FC range of 30 μM are −5.03 to −0.26 and 0.27 to 8.85.
