Table 4.

Univariable analysis of disease recurrence, CSM and OM in 255 elderly patients treated with RC for UBC

		Recurrence		CSM		OM
		Cox regression		Cox regression		Cox regression
Univariable analysis		HR (95% CI)	P	HR (95% CI	P	HR (95% CI)	P
ASA score		0.84 (0.38–1.23)	0.38	1.38 (0.83–2.28)	0.21	1.04 (0.74–1.47)	0.78
ECOG PS score		1.39 (0.99–1.95)	0.06	1.39 (0.93–2.08)	0.10	1.46 (1.10–1.94)	0.008
Age at RC		1.02 (0.99–1.05)	0.11	1.05 (1.01–1.09)	0.01	1.09 (1.06–1.12)	<0.001
CCI score		1.02 (0.89–1.18)	0.72	0.95 (0.78–1.45)	0.59	0.92 (0.80–1.05)	0.24
Preoperative hydronephrosis		1.002 (0.87–1.15)	0.97	1.06 (0.64–1.78)	0.80	1.21 (0.98–1.93)	0.08
Preoperative haemoglobin		1.10 (0.71–1.71)	0.67	0.94 (0.81–1.10)	0.49	0.95 (0.85–1.06)	0.41
Preoperative eGFR		0.99 (0.99–1.00)	0.97	1.00 (0.99–1.01)	0.30	0.99 (0.99–1.01)	0.06
Preoperative BMI		1.01 (0.97–1.06)	0.60	1.01 (0.96–1.06)	0.72	1.02 (1.00–1.03)	0.05
Preoperative total cholesterol		1.00 (0.99–1.00)	0.76	1.00 (0.99–1.00)	0.63	1.00 (0.99–100)	0.81
Preoperative HDL		0.99 (0.97–1.01)	0.36	0.98 (0.96–1.01)	0.13	0.99 (0.97–1.01)	0.39
NLR (>3 vs ≤3)		1.36 (1.07–1.71)	0.01	1.59 (1.18–2.13)	0.002	1.34 (1.01–1.77)	0.04
Preoperative fibrinogen		1.009 (1.005–1.012)	<0.001	1.007 (1.003–1.010)	0.02	1.003 (0.998–1.009)	0.034
Preoperative albumin		0.64 (0.39–0.99)	0.045	0.48 (0.27–0.68)	0.001	0.65 (0.42–0.89)	0.001
Preoperative CRP (mg/L)		1.23 (1.15–1.32)	<0.001	1.19 (1.10–1.30)	<0.001	1.05 (0.99–1.10)	0.08
mGPS	1 vs 0	3.14 (1.78–5.33)	<0.001	3.53 (2.11–9.51)	<0.001	1.12 (0.71–1.78)	0.61
	2 vs 0	4.40 (4.33–12.57)	<0.001	4.73 (2.19–10.12)	<0.001	1.68 (1.11–2.54)	1.78
pT3–4 vs pT1–2		5.51 (4.26–8.67)	<0.001	4.27 (2.39–5.76)	<0.001	0.90 (0.61–1.34)	0.62
pN+		1.71 (1.12–2.62)	0.01	2.32 (1.75–3.44)	<0.001	2.11 (1.32–2.81)	0.004
Concomitant CIS at RC specimen		1.34 (0.93–1.91)	0.11	1.34 (0.93–1.91)	0.11	1.34 (0.93–1.91)	0.11
LVI at RC specimen		1.87 (1.17–3.02)	0.02	1.65 (1.02–2.66)	0.04	1.29 (0.82–2.02)	0.26