Table 5.
Multivariable analysis for disease recurrence, CSM and OM in 255 elderly patients treated with RC for UBC
| Recurrence |
CSM |
OM |
|||||
|---|---|---|---|---|---|---|---|
| Competing-risk regression |
Competing-risk regression |
Cox regression |
|||||
| Multivariable analysis | SHR (95% CI) | P | SHR (95% CI) | P | HR (95% CI) | P | |
| ASA score | - | - | - | - | - | - | |
| ECOG PS score | - | - | 1.26 (0.79–2.00) | 0.33 | 1.18 (0.75–1.87) | 0.46 | |
| Age at RC | 1.02 (0.99–1.04) | 0.23 | - | - | 1.04 (1.01–1.08) | 0.001 | |
| CCI score | - | - | - | - | - | - | |
| Preoperative hydronephrosis | - | - | - | - | - | - | |
| Preoperative haemoglobin | - | - | - | - | - | - | |
| Preoperative creatinine | - | - | - | - | - | - | |
| Preoperative eGFR | - | - | - | - | - | - | |
| Preoperative BMI | - | - | - | - | - | - | |
| Preoperative total cholesterol | - | - | - | - | - | - | |
| Preoperative HDL | - | - | - | - | - | - | |
| NLR >3 | 1.13 (0.96–1.32) | 0.14 | 1.21(0.99–1.48) | 0.06 | 1.38 (1.01–1.77) | 0.01 | |
| Preoperative fibrinogen | 1.005 (1.002–1.009) | 0.001 | 1.003 (1.001–1.008) | 0.001 | - | - | |
| Preoperative albumin | - | - | - | - | 0.63 (0.49–0.92) | 0.001 | |
| Preoperative CRP (mg/L) | - | - | - | - | - | - | |
| mGPS | 1 vs 0 | 2.96 (1.72–6.28) | 0.01 | 2.26 (2.16–5.82) | 0.001 | - | - |
| 2 vs 0 | 2.48 (2.50–7.35) | 0.01 | 2.44 (2.37–6.13) | 0.001 | - | - | |
| pT3–4 vs pT1–2 | 4.58 (2.61–9.37) | 0.001 | 2.57 (1.39–5.76) | <0.001 | 1.49 (1.19–5.76) | <0.001 | |
| pN+ | 3.52 (2.46–6.27) | 0.004 | 3.36 (1.76–3.45) | <0.001 | 3.36 (1.75–3.44) | <0.001 | |
| Concomitant CIS at RC specimen | - | - | - | - | - | - | |
| LVI at RC specimen | 1.78 (1.06–2.99) | 0.03 | 1.48 (0.99–2.17) | 0.05 | - | - | |
| C-index | 0.734 | 0.739 | 0.712 | ||||