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. 2021 Mar 15;131(6):e143557. doi: 10.1172/JCI143557

Figure 4. Clinical data from patients with breast cancer corroborate HER2:PIK3CA clonal dynamics.

Figure 4

(A) Schematic of the patient selection criteria for the cBioPortal-based analysis of the GENIE cohort v7.0. (B) Allelic frequencies of HER2 (red) and PIK3CA (green) in breast tumors that had a cooccurrence of HER2 and PIK3CA mutations, sorted by HER2 allele frequency. The gray box indicates patients with HER2 allele frequency less than 0.5. For further information on patient samples, see Supplemental Table 2.