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. 2021 Mar 15;131(6):e144554. doi: 10.1172/JCI144554

Figure 4. Quantitative circulating levels of selected cytokines.

Figure 4

Quantitative levels of cytokines with significant differences between MIS-C (n = 7) and MIS-Cplus (n = 5) are shown. Open symbols represent plasma samples and filled symbols are serum samples. Bars represent median values. Described values for IFN-γ in (i) viral infections range from 7.7 to 33.4 pg/mL (33); (ii) suspected primary hemophagocytic syndrome with or without genetic confirmation range from 147.6 to >5000 pg/mL (33) and a mean (95% CI) of 905.7 pg/mL (530.7–1280.6 pg/mL, ref. 35); and (iii) patients with MAS in systemic-onset juvenile idiopathic arthritis mean (IQR) of 15.4 pg/mL (5.1–52.6 pg/mL, ref. 36). KD, pre–SARS-CoV-2 pandemic Kawasaki disease (n = 14); MIS-C, multisystem inflammatory syndrome in children (n = 13); COVID, pediatric patients with mild COVID-19 disease without MIS-C (n = 9); HC, healthy controls (n = 37 [53 samples]).