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. 2021 Feb 6;147(4):1007–1017. doi: 10.1007/s00432-021-03536-3

Fig. 1.

Fig. 1

TERT chromosomal location and regulative motives. Schematic illustration showing the TERT promoter with the novel ETS1 binding sites and cancer-specific TERT promoter mutations C250T and C228T. -146 and -124 indicate the position of the C250T and C228T mutations upstream, respectively, in relation to the start of the TERT coding sequence ATG, indicated as + 1. WT wild-type MT mutation