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. 2021 Mar 12;38(4):36. doi: 10.1007/s12032-021-01482-1

Fig. 2.

Fig. 2

Receiver operating characteristics curve for different CN threshold values. For lower threshold values, the pipeline calls everything as amplified, which are all false positives (x axis); for higher threshold cutoff values, our ability to correctly call real events decreases. A threshold of 3.2 has the best sensitivity and specificity