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. 2020 Dec 10;147(4):1031–1040. doi: 10.1007/s00432-020-03486-2

Table 4.

Multivariate cox-regression analysis for all patients and for those with/without neoadjuvant treatment

Factor All patients Patients with neoadjuvant treatment Patients without neoadjuvant treatment
Hazard ratio 95% confidence interval p value Hazard ratio 95% confidence interval p value Hazard ratio 95% confidence interval p value
Lower Upper Lower Upper Lower Upper
Sex: male versus female 1.181 0.727 1.918 0.501 1.558 0.836 2.902 0.162 0.481 0.216 1.072 0.074
Age groups: < 65yrs versus > 65 years 1.273 0.980 1.655 0.071 1.170 0.838 1.632 0.357 1.662 1.038 2.662 0.034
Tumor stage:pT1/2 versus pT3/4 1.434 0.992 2.073 0.055 0.874 0.550 1.391 0.571 2.629 1.403 4.924 0.03
Lymph node metastasis: pN0 versus pN +  2.863 2.106 3.981 0.001 2.197 1.504 3.210 0.001 4.294 2.509 7.351 0.001
GATA6:negative versus positive 0.745 0.470 1.181 0.210 0.897 0.558 1.443 0.655 0.001 0.000 10.000 0.961