Table A.1.

Basic patient information.

Case	Family data	Basic data	Symptom onset date		Symptoms	Confirmation date
A1	Residents of Wuhan, arrived in Guangzhou on Jan. 22. Family A includes four small families: the family of the index case including their husband and grandson (n = 3); mother-in-law's family (n = 2); sister's family (n = 2); and niece's family (n = 3)	female, 63 y.o., history of hypertension, hyperlipidemia, and cervical spondylosis.	Jan. 24		Fever (37.5 °C), dry cough	Jan. 26
A2		female, 60 y.o., younger sister of case A1, was in good health.	Jan. 27		Fever (37.8 °C)	Jan. 27
A3		female, 62 y.o., mother-in-law of A1's son, was in good health.	Jan. 29		Fever (37.3 °C)	Jan. 30
A4		female, 34 y.o., niece of A1, was in good health.	Jan. 29		Fever (not recorded)	Jan. 30
A5		male, 63 y.o., father-in-law of A1's son, was in good health.	Feb. 2		Fever (not recorded)	Feb. 3
B1	Residents of Guangzhou. Family B (n = 4) includes one family, although the older mother lived alone.	female, 44 y.o., was in good health.	Feb. 1	Fever (38.4 °C), cough, sputum		Feb. 4
B2		female, 20 y.o., daughter of B1, was in good health.	Feb. 3		diarrhea and fever (38.6 °C), dry cough, chest tightness, asthma	Feb. 6
B3		male, 53 y.o., husband of B1, was in good health.	Feb. 5		headache, chest tightness, chest pain, bloating	Feb. 6
C1	Residents of Guangzhou. Family C includes three small families: the patient couple and mother (n = 3); their son's family (n = 2); and brother's family (n = 2).	female, 82 y.o., retired, was in good health.	Jan. 27		Fever (37.8 °C), runny nose, cough, sputum	Feb. 10
C2		female, 54 y.o., daughter of C1, was in good health.	Jan. 31		fever (39.9 °C), dry cough	Feb. 6