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. 2021 Mar 12;11:5817. doi: 10.1038/s41598-021-85089-6

Figure 1.

Figure 1

DUSP3 genetic deletion promotes obesity. (a) Representative images of 18-month-old WT and DUSP3-KO mice fed CD (left photo) and 5-month-old WT and DUSP3-KO mice fed HFD (right photo). (b) WT and KO mice were fed chow diet (left panel) or HFD (right panel) and body weight was monitored weekly during 60 weeks. The data are expressed as means ± SD (n = 10 mice in each group). (c) Weight gain of WT and KO mice after 60 weeks of CD or HFD. (d) Food intake during 27 weeks for WT and KO mice under CD and HFD. (e) Representative CT-scan images of 5- and 18-month-old WT and KO mice under CD and HFD. The white color represents fat and dark represent lean mass. (f) Quantification of fat body mass [n = 3 mice in each group shown in (e)] Data represent the mean ± SD of at least three mice of each group (*P < 0.5; **P < 0.01).