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. Author manuscript; available in PMC: 2022 Apr 1.
Published in final edited form as: Trends Biochem Sci. 2020 Dec 18;46(4):284–300. doi: 10.1016/j.tibs.2020.10.004

Figure 1 (Key figure) -. The feedback between glycan dependent receptor sensing and glycan biosynthesis regulate cellular communication and environmental response.

Figure 1 (Key figure) -

Here we discuss (A) the system-level impacts of glycosylation, (B) tools to study glycan biosynthesis given various data types, and (C) databases and analytical strategies to explore the dynamic co-regulatory systems of glycan biosynthesis and intercellular communication. Diverse bioinformatics approaches and resources are now making it easier to consider glycosylation in diverse research fields.