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. Author manuscript; available in PMC: 2021 Aug 15.
Published in final edited form as: Nat Methods. 2021 Feb 15;18(3):283–292. doi: 10.1038/s41592-021-01060-3

Fig. 2 |. Histone modification-based cell-clustering recapitulate transcriptomic -based cell clustering with varying degrees of success.

Fig. 2 |

a, UMAP-embedding from single-nucleus histone modification profiles. b, UMAP-embedding from single-nucleus joint histone modification and nuclear transcriptome profiles. Each dot represents an individual nucleus profiled by Paired-Tag and was colored by cell type annotations from the joint clustering. c, Sankey plots showing the overlap between cell clustering based on Paired-Tag histone modification profiles, RNA profiles and joint modalities for H3K4me1, H3K4me3, H3K27ac, H3K27me3 and H3K9me3 DNA datasets.