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. 2021 Jan 3;37(3):298–310. doi: 10.1007/s12264-020-00618-z

Fig. 6.

Fig. 6

Reduced dendritic complexity in CA1 and DG after Foxg1 overexpression. A, B Representative images showing the morphology of granule cells at P17 in control and TG mice by Golgi staining. C Total dendritic length is significantly reduced in NEX-cre;Foxg1 TG mice (control, n = 38 cells from 5 mice; TG, n = 36 cells from 5 mice, ****P < 0.0001; t-test). D Sholl analysis of the dendritic complexity of granule cells (control, n = 38 cells from 5 mice; TG, n = 36 cells from 5 mice, ***P < 0.0001; two-way ANOVA). E, F Representative images of Golgi-stained CA1 pyramidal neurons from control (E) and TG (F) mice. G Total dendritic length of CA1 pyramidal neurons is also reduced in TG mice (control, n = 38 cells from 5 mice; TG, n = 30 cells from 5 mice, ****P < 0.0001; t-test). H Sholl analysis of the dendritic complexity of hippocampal CA1 pyramidal neurons (control, n = 38 cells from 5 mice; TG, n = 30 cells from 5 mice; ***P < 0.0001; two-way ANOVA). CA, cornu ammonis; scale bars, 20 μm.