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Permeability results of test compounds in MDCK cell line
| Compound | Papp (A-B) (10−6, cm/s) | Papp (B-A) (10−6, cm/s) | Efflux ratio | Recovery (%) AP-BL | Recovery (%) BL-AP |
|---|---|---|---|---|---|
| Metoprolol | 26.9 | 21.2 | 0.79 | 90.7 | 90.4 |
| Digoxin | 1.08 | 5.41 | 5.01 | 77.1 | 83.7 |
| Imatinib | 7.69 | 6.50 | 0.84 | 56.6 | 69.9 |
| 3 | 20.1 | 9.52 | 0.47 | 52.4 | 49.8 |
