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. 2021 Feb 13;10(1):621–630. doi: 10.1007/s40121-021-00412-y
Why carry out this study?
Guidelines for treatment of multidrug-resistant (MDR) bacteria rely on newly approved antibiotics.
We aimed to assess how much would it cost to base treatment for multidrug-resistant bacterial infections on those new antibiotics.
What was learned from the study?
Annual incremental cost of new antibiotics could reach 30–500 million USD for some bacteria.
Lack of solid evidence for superior effectiveness of new antibiotics for these bacteria complicates treatment decisions.
Cost should be part of the discussion while considering use of newly approved antibiotics until further evidence for effectiveness accumulates.