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. 2021 Mar 12;11:5838. doi: 10.1038/s41598-021-84708-6

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Upregulation of EZH2 target genes. (a) Correlation of protein and mRNA expression. Dark grey points representing genes differentially expressed in both measures (adj.P < 0.05). Pearson’s correlation. (b) Heatmap of the 41 genes differentially expressed (adj.P < 0.05) between EZH2^−/− and wild type clones, in both protein and mRNA. The colour gradient from red to blue represents high to low expression of genes. White indicates no change.