Table 1.
Comparison of clinicopathological factors between patients with normal weight and overweight following the hepatic resection of intrahepatic cholangiocarcinoma.
| Factors | BMI < 25 kg/m2 (n = 48) | BMI ≥ 25 kg/m2 (n = 26) | P value |
|---|---|---|---|
| Age (yr) | 66 (39–87) | 67 (44–85) | 0.5826 |
| Sex (male/female) | 33/15 | 18/8 | 0.9660 |
| HBV (+ , %) | 3 (6.3%) | 4 (15.4%) | 0.1999 |
| HCV (+ , %) | 6 (12.5%) | 0 (0.0%) | 0.6000 |
| NASH (+ , %) | 5 (10.4%) | 4 (15.4) | 0.5325 |
| Hypertension (+ , %) | 14 (29.2%) | 19 (73.1%) | 0.0002* |
| Type 2 diabetes (+ , %) | 7 (14.6%) | 7 (26.9%) | 0.1957 |
| Fasting glucose (mg/dL) | 99 (71–247) | 99.5 (89–277) | 0.3779 |
| Fasting triglycerides (mg/dL) | 83 (33–384) | 99.5 (60–290) | 0.1453 |
| Albumin (g/dL) | 4.1 (3.3–5.3) | 4.1 (3.5–4.8) | 0.8290 |
| Total bilirubin (mg/dL) | 0.8 (0.2–1.7) | 0.7 (0.3–1.1) | 0.7025 |
| Platelets (× 104/μL) | 19.8 (5.2–44.0) | 17.7 (7.4–40.2) | 0.7002 |
| Total lymphocytes (× 103/uL) | 1.5 (0.4–4.0) | 1.6 (0.8–2.8) | 0.2458 |
| CA19-9 (U/mL) | 21.5 (0.6–40,795) | 42.9 (0.6–21,100) | 0.0337* |
| Tumor size (cm) | 3.5 (0.5–12.0) | 5.4 (1.8–10.0) | 0.0292* |
| Poor differentiation (%) | 30 (62.5%) | 14 (53.9%) | 0.4692 |
| Microvascular invasion (%) | 19 (39.6%) | 16 (61.5%) | 0.0709 |
| Bile duct invasion (%) | 18 (37.5%) | 13 (50.0%) | 0.2981 |
| Intrahepatic metastasis (%) | 10 (20.8%) | 15 (57.7%) | 0.0014* |
| Lymph node metastasis (%) | 6 (12.5%) | 7 (26.9%) | 0.1196 |
| Histological liver cirrhosis (%) | 7 (14.6%) | 3 (11.5%) | 0.7145 |
Data are presented as n (%) or the median (range).
BMI, body mass index; CA19-9, carbohydrate antigen 19-9; HBV, hepatitis B virus; HCV, hepatitis C virus; NASH, non-alcoholic steatohepatitis, *P < 0.05.