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. 2021 Mar 12;5(1):NS20200011. doi: 10.1042/NS20200011

Table 3. Summary of the behavioural similarities between human DS and mouse models of DS.

DS (Human) Ts65Dn Dep(17)1Yey/+ Dep(10)1Yey/+ Ts1Yah
Spatial context discrimination = =
Spatial learning and memory = =
Working memory

Ts65Dn animals share many similar deficits (down arrow) in learning and memory with human DS compared with control, while some other mouse models are either unaffected (=) or enhanced (up arrow) compared with control. Adapted from [78].