Fig. 3. The machine learning pipeline used to build aptardi is robust to different data sets and the aptardi prediction model generated from the Human Brain Reference data set is applicable across diverse data sets.

Blue bars indicate the performance of the data set-specific prediction model on its own data set, i.e., the model was built and evaluated on a single data set. Orange bars represent the performance of the aptardi prediction model—built from the Human Brain Reference data set—on the given data set (x axis).