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. 2021 Mar 12;11:5850. doi: 10.1038/s41598-021-84034-x

Table 1.

List of movement biomarkers having at least 3 COSMIN items assessed in the included studies. Biomarkers for which all these items reached at least a good level (see Table 4 for measurement properties rating) are in bold.

ID Variable name Task Reliability Validity Interpr Clinical appl Study
R1 R2 V1 V2 V3 MDC
BMo3 Hip sagittal angle (rom) Sit to stand +/++ NA +++ NA ++ + Pourahmadi et al., 201857
BMo4 Hip sagittal angle (rom) Stand to sit ++/++ NA +++ NA ++ + Pourahmadi et al., 201857
BMo5 Lower lumbar sagittal angle (max) Trunk sagittal bending +++/++ NA +++ NA +++ + Hidalgo et al., 201225
BMo6 Lower lumbar sagittal angular velocity (max) Trunk sagittal bending +++/++ NA +++ NA ++ + Hidalgo et al., 201225
BMo9 Lower thorax sagittal angle (max) Trunk sagittal bending ++/+++ NA +++ NA +++ + Hidalgo et al., 201225
BMo10 Lumbar contribution to thorax angle (rom) Trunk sagittal bending NA NA +++ NA + + Laird et al., 201642
BMo12 Lumbar sagittal angle (max) Trunk sagittal bending +++/++ NA ++ NA ++ + Hidalgo et al., 201225, 201358
BMo17 Lumbar sagittal angular velocity (max) Trunk sagittal bending +++/++ NA +++ NA +++ + Hidalgo et al., 201225
BMo19 Lumbar transversal angle (max) Trunk rotation ++/++ ++/++ +++ NA + NA + Haj et al., 201959
BMo20 Lumbar transversal angular acceleration (max) Trunk rotation ++/++ ++/++ +++ NA + NA + Haj et al., 201959
BMo21 Lumbar transversal angular velocity (max) Trunk rotation ++/++ ++/++ +++ NA + NA + Haj et al., 201959
BMo22 Lumbar transversal angular velocity (mean) Trunk rotation ++/++ ++/++ +++ NA + NA + Haj et al., 201959
BMo23 Lumbar/hip ratio of sagittal angle (rom) Sit to stand +/+ NA +++ NA ++ + Pourahmadi et al., 201857
BMo24 Lumbar/hip ratio of sagittal angle (rom) Stand to sit +/++ NA +++ NA ++ + Pourahmadi et al., 201857
BMo25 Lumbar/hip relative phase difference (max) Sit to stand ++/++ NA +++ NA ++ + Pourahmadi et al., 201857
BMo26 Lumbar/hip relative phase difference (mean) Sit to stand +/++ NA +++ NA + + Pourahmadi et al., 201857
BMo27 Lumbar/hip relative phase difference (mean) Stand to sit +/++ NA +++ NA + + Pourahmadi et al., 201857
BMo28 Lumbar/hip relative phase difference (min) Sit to stand +/+ NA +++ NA ++ + Pourahmadi et al., 201857
BMo29 Lumbar/pelvis absolute relative phase (mean) Trunk sagittal bending +/+ NA +++ NA ++ NA + Mokhtarinia et al., 201660
BMo30 Lumbar/pelvis deviation phase (mean) Trunk sagittal bending +/+ NA +++ NA + NA + Mokhtarinia et al., 201660
BMo33 Lumbopelvic sagittal angle (rom) Sit to stand ++/+ NA +++ NA ++ + Pourahmadi et al., 201857
BMo34 Lumbopelvic sagittal angle (rom) Stand to sit +/+ NA +++ NA ++ + Pourahmadi et al., 201857
BMo37 Pelvis sagittal angle (max) Trunk sagittal bending NA ++/++ ++ NA ++ NA +++ Neblett et al., 201337
BMo42 Pelvis/thigh deviation phase (mean) Trunk sagittal bending +/+ NA +++ NA ++ NA + Mokhtarinia et al., 201660
BMo43 Scapular belt transversal angle (max) Trunk rotation ++/++ NA +++ NA ++ + Hidalgo et al., 201225
BMo44 Thoracopelvic sagittal angle (max) Trunk sagittal bending NA ++/++ ++ NA ++ NA ++

Ahern et al., 198861; Larivière et al., 201162;

Neblett et al., 201337

BMo49 Thorax sagittal angle (max) Trunk sagittal bending NA ++/++ ++ NA ++ NA +++ Neblett et al., 201337
BMo57 Upper lumbar sagittal angle (max) Trunk sagittal bending +++/++ NA +++ NA +++ + Hidalgo et al., 201225
BMo58 Upper lumbar sagittal angular velocity (max) Trunk sagittal bending +++/++ NA +++ NA +++ + Hidalgo et al., 201225
BMo59 Upper thorax sagittal angle (max) Trunk sagittal bending ++/+++ NA +++ NA +++ + Hidalgo et al., 201225
BMo80 Lumbopelvic sagittal angle (max) Trunk sagittal bending +++/NA NA +++ NA +++ + Matheve et al., 201963

R1: Intra-observer reliability (controls/patients); R2: Inter-observer reliability (controls/patients); V1: Content validity; V2: Criterion validity; V3: Construct validity, rom: range of motion, max: maximum.

min: minimum, MDC: minimum detectable change, interp.: interpretability, appl.: applicability, in bold: biomarkers for which all items reached at least a good level (see Table 1 for measurement properties rating).

+++: Excellent; ++: Good; +: Moderate; ●: available; NA: not available (see Table 4 for measurement properties rating).