Table 2. Results of the subgroup analysis on prognostic significance of GRNI in HF.
| Analysis | Categories | No of Studies (n) | Patients (n) | Model | HR (95%CI) | Z | p | I2 (%) | ph |
|---|---|---|---|---|---|---|---|---|---|
| Overall | 9 | 7659 | Random | 1.59 (1.37, 1.85) | 5.96 | 0.00 | 93.40 | 0.00 | |
| Study region | Western country | 3 | 5206 | Random | 2.78 (1.86, 4.17) | 4.95 | 0.00 | 58.70 | 0.08 |
| Eastern country | 6 | 2453 | Random | 1.21 (1.09, 1.34) | 3.58 | 0.00 | 85.80 | 0.00 | |
| Sample size | >500 | 3 | 6337 | Random | 2.24 (1.20, 4.18) | 2.52 | 0.01 | 95.00 | 0.00 |
| ≤500 | 6 | 1332 | Random | 1.13 (1.03, 1.24) | 2.57 | 0.01 | 76.30 | 0.00 | |
| Age | >75 years | 4 | 1108 | Random | 1.91 (1.07, 3.38) | 2.21 | 0.02 | 79.50 | 0.00 |
| ≤75 years | 5 | 6551 | Random | 1.82 (1.21, 2.73) | 2.89 | 0.00 | 97.00 | 0.00 | |
| Follow-up duration | >2 years | 5 | 6632 | Random | 2.23 (1.35, 3.68) | 3.14 | 0.00 | 90.60 | 0.00 |
| ≤2 years | 4 | 1027 | Random | 1.09 (1.02, 1.17) | 2.48 | 0.01 | 72.10 | 0.01 | |
| HF type | Acute HF | 2 | 704 | Random | 1.07 (1.05, 1.09) | 6.24 | 0.00 | 0.00 | 0.36 |
| HFpEF | 3 | 1939 | Random | 2.46 (1.88, 3.21) | 6.61 | 0.00 | 0.00 | 0.81 | |
| Mixed | 4 | 5106 | Random | 2.10 (1.07, 4.12) | 2.15 | 0.03 | 91.70 | 0.00 |
GRNI geriatric nutritional risk index; HF heart failure; HFpEF heart failure with preserved ejection fraction; HR hazard ratios; CI confidence interval; ph p value of heterogeneity.