Table 4.
Factors Correlating with Major Adverse Cardiac Events During Follow‐Up
| Univariable Analysis | Multivariable Analysis | |||||
|---|---|---|---|---|---|---|
| Unadjusted HR | 95%CI | P Value | Adjusted HR | 95%CI | P Value | |
| Age >75 y | 0.47 | 0.06 to 3.55 | 0.46 | |||
| Male | 8.82 | 1.16 to 67.11 | 0.04 | |||
| Hypertension | 1.60 | 0.55 to 4.70 | 0.39 | |||
| Diabetes mellitus | 1.30 | 0.44 to 3.80 | 0.63 | |||
| Dyslipidemia | 1.88 | 0.67 to 5.29 | 0.23 | |||
| Current smoking | 5.01 | 1.71 to 14.67 | <0.01 | 3.25 | 1.04 to 10.11 | 0.04 |
| Chronic kidney disease | 2.27 | 0.51 to 10.06 | 0.28 | |||
| Atrial fibrillation | 0.51 | 0.07 to 3.87 | 0.51 | |||
| Previous MI | 1.69 | 0.38 to 7.51 | 0.49 | |||
| BNP >100 pg/mL | 2.54 | 0.72 to 9.01 | 0.15 | |||
| LVEF <50% | 0.82 | 0.11 to 0.63 | 0.85 | |||
| VSA | 4.96 | 0.65 to 37.74 | 0.12 | |||
| Multivessel spasm | 2.53 | 0.90 to 7.11 | 0.08 | |||
| Multivessel organic stenosis | 12.03 | 4.27 to 33.90 | <0.01 | 3.40 | 0.91 to 12.74 | 0.07 |
| Spasm at organic stenosis | 4.41 | 1.60 to 12.15 | <0.01 | |||
| Low‐FFR group | 8.53 | 3.09 to 23.6 | <0.01 | 3.94 | 1.14 to 13.59 | 0.03 |
BNP indicates B‐type natriuretic peptide; CI, confidence interval; FFR, fractional flow reserve; HR, hazard ratio; LVEF, left ventricular ejection fraction; MI, myocardial infarction; and VSA, vasospastic angina.