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. 2020 Dec 5;9(24):e018418. doi: 10.1161/JAHA.120.018418

Figure 6. Immunohistochemistry staining for Ki‐67 and TUNEL.

Figure 6

A, Representative staining for Ki‐67 at day 28. Cells staining brown are positive for Ki‐67. B, Representative staining for TUNEL. Cells staining black are positive for TUNEL. C, Semiquantitative analysis showed a significant decrease in the average Ki‐67 positive index in the SV‐treated vessels compared with control and MP groups (C N=5, MP N=5, SV N=6). D, Semiquantitative analysis showed a significant increase in the average TUNEL positive staining in SV‐treated vessels compared with control group and MP group (Control N=6, MP N=5, Simvastatin N=6). Two‐sample t test was performed (C and D). Each bar represents mean±SD. Significant differences are indicated by *P<0.05 and **P<0.01. Scale bar is 50 μm. C indicates controls; dUTP, deoxyuridine triphosphate; MP, microparticles; SV, simvastatin; and TUNEL, terminal deoxynucleotidal transferase–mediated biotin–deoxyuridine triphosphate nick‐end labeling.